One bowl, bold Southwest flavor, and zero fuss — that's exactly what this Salsa Meatloaf delivers on a busy weeknight. Instead of the usual ketchup glaze, this meatloaf with salsa builds big flavor right into the meat mixture and finishes with a melted cheese topping that makes it feel special. It's the kind of spicy meatloaf recipe that earns a permanent spot in your dinner rotation without asking much of you at all.